Patent · US Active

Nitrogenous tricyclic compounds and uses thereof in medicine

US11208418B2 · kind B2 · utility

0Cited by
30References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 28, 2019
Grant dateDec 28, 2021
Priority date
Expiry dateJan 28, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/107
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Nitrogenous tricyclic compounds and uses thereof in medicine, in particular, a novel nitrogenous tricyclic compound used as an FXR active regulator and a stereoisomer, a geometrical isomer, a tautomer, a N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and use of the compound in the manufacture of a drug for treating a disease and/or disorder regulated by FXR. A pharmaceutically acceptable composition containing the compound and a method of treating a disease and/or disorder mediated by FXR comprising administering the compound or pharmaceutical composition thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.