Phenylbenzofuran compound, preparation method therefor, composition containing the same and medical application thereof
US11208419B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 17, 2019 |
| Grant date | Dec 28, 2021 |
| Priority date | — |
| Expiry date | Jan 17, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA23V2002/00
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The invention discloses a phenylbenzofuran compound, preparation method therefor, composition containing the same and medical application thereof. The phenylbenzofuran compound is represented by the formula The preparation method includes a traditional Chinese medicine extraction method by using Sophorae Tonkinensis Radix Et Rhizoma coarse powder as a raw material, and a chemical synthesis method. Active component of the composition is phenylbenzofuran compound, and composition is a drug, food or health product. The application of the phenylbenzofuran compound in the preparation of a drug, a food or health product for preventing or treating a tumor, wherein the tumor is nasopharyngeal carcinoma. The phenylbenzofuran compound is prepared by traditional Chinese medicine extraction method and chemical synthesis method. It has been proved that phenylbenzofuran has certain inhibition effect on nasopharyngeal carcinoma cells CNE-1 and CNE-2 by tumor cell experiments in vitro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.