Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles
US11208437B2 · kind B2 · utility
2Cited by
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27Claims
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Key dates
| Filing date | Dec 23, 2019 |
| Grant date | Dec 28, 2021 |
| Priority date | — |
| Expiry date | Dec 31, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/10332
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates generally to bacterial delivery vehicles for use in efficient transfer of a desired payload into a target bacterial cell. More specifically, the present disclosure relates to bacterial delivery vehicles with desired host ranges based on the presence of a chimeric receptor binding protein (RBP) composed of a fusion between the N-terminal region of a RBP derived from a lambda-like bacteriophage and the C-terminal region of a different RBP, and/or the presence of an engineered branched receptor binding multi-subunit polypeptides (“branched-RBP”).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.