PD-1 single domain antibodies and therapeutic compositions thereof
US11208485B2 · kind B2 · utility
0Cited by
33References
28Claims
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Assignee
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Key dates
| Filing date | Oct 11, 2019 |
| Grant date | Dec 28, 2021 |
| Priority date | — |
| Expiry date | Oct 11, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are binding polypeptides that specifically bind PD-1. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific constructs and chimeric antigen receptors, that bind PD-1. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided PD-1 binding polypeptides for treating diseases and conditions, such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.