Variable index for determining patient status
US11213258B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 7, 2018 |
| Grant date | Jan 4, 2022 |
| Priority date | — |
| Expiry date | Aug 16, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16H50/20
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods are disclosed for determining a prognosis of a test patient following or during a surgical procedure. In some embodiments, the disclosed methods comprise forming a test data vector characterizing concurrent measures of mean arterial pressure (MAP), bispectral index (BIS), and standard minimum alveolar concentration (MAC) of the test patient from sequential time intervals during the surgical procedure. A K-means clustering procedure is performed on the test data vector and a plurality of reference data vectors characterizing concurrent MAP, BIS, and MAC measures for sequential time intervals during surgical procedures from reference patients with known clinical outcome. A prognosis of one or more post-surgical outcomes of the test patient is determined based on the known surgical outcome of reference patients in the cluster including the test data vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.