Patent · US Active

Vascularized biphasic tissue constructs

US11213614B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

The George Washington University · US

Inventors

Lijie Zhang · Suwon-si, KR
Haitao Cui · Arlington, US
Wei Zhu · Shanghai, CN

Key dates

Filing date	Mar 20, 2018
Grant date	Jan 4, 2022
Priority date	—
Expiry date	Mar 20, 2038

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/40
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Biphasic tissue constructs that include a scaffold having one or more channels, a vascular portion comprising a hydrogel at least partially disposed in the one or more channels, and a first bioactive growth factor and a second bioactive growth factor different from the first bioactive growth factor, the first bioactive growth factor localized to the scaffold and the second bioactive growth factor localized to the vascular portion. The first bioactive growth factor may be bone morphogenetic protein 2 (BMP2) peptide and the second bioactive growth factor may be vascular endothelial growth factor (VEGF) peptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.