Patent · US Active

Charge-reversed N-terminal spider silk protein domain and uses thereof

US11214601B2 · kind B2 · utility

0Cited by

2References

19Claims

0Family size

Assignee

SPIBER TECHNOLOGIES AB · SE

Inventors

Jan Johansson · Stockholm, SE
Anna Rising · Uppsala, SE
Nina Kronqvist · Kramfors, SE
Kerstin Nordling · Knivsta, SE

Key dates

Filing date	Mar 12, 2020
Grant date	Jan 4, 2022
Priority date	—
Expiry date	Mar 12, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/35
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A protein comprising a moiety of 100-160 amino acid residues having at least 70% identity with the N-terminal (NT) fragment of a spider silk protein, wherein the amino acid residue corresponding to position 40 in NT is selected from the group consisting of Lys, Arg and His; and wherein the amino acid residue corresponding to position 65 in NT is selected from the group consisting of Asp and Glu, is useful as a moiety in a fusion protein for enhancing the solubility of another moiety in the fusion protein, which is a desired protein or polypeptide.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.