Method of crosslinking glycosaminoglycans
US11214655B2 · kind B2 · utility
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Key dates
| Filing date | Aug 2, 2017 |
| Grant date | Jan 4, 2022 |
| Priority date | — |
| Expiry date | Aug 2, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L2312/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new hydrogel made of crosslinked glycosaminoglycans, particularly crosslinked hyaluronic acid, chondroitin or chondroitin sulfate, having reversible linkages using boronic acid or boroxole derivatives leading to new benefits. Glycosaminoglycans that are crosslinked via an alkoxyboronate ester anion formed between a diol portion of a diol-functional moiety grafted to a first glycosaminoglycan and a boronate hemiester grafted to a second glycosaminoglycan.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.