Method for making a micronized dry powder formulation of glycopyrrolate and magnesium stearate
US11219602B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Mar 14, 2018 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Mar 14, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/573
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are disclosed for simultaneously jet milling and conditioning particulate glycopyrrolate and magnesium stearate using a milling gas having humidity between 5% and 30% Relative Humidity in the grinding chamber of a jet mill, the jet mill is configured with a humidifier arranged to supply humidity into the grinding chamber. A composition and formulation comprising physically stable micronized composite glycopyrrolate particles made by this method is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.