Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
US11219634B2 · kind B2 · utility
9Cited by
42References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 21, 2016 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Nov 9, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F293/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include administering to the subject an effective amount of a lipid nanoparticle comprising the therapeutic or diagnostic agent and an effective amount of a membrane-destabilizing polymer. Also disclosed are related compositions and delivery systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.