Total flavonoid extract from Gynura formosana Kitam., preparation method thereof, and use of same in treating non-alcoholic fatty liver disease

US11219654B2 · kind B2 · utility

Assignee

• ZHANGZHOU PIEN TZE HUANG PHARMACEUTICAL CO., LTD. · CN

Inventors

• Zhiliang Chen · Shanghai, CN
• Jinming Huang · Lo Wu, CN
• Juan Yu · Fujian, CN
• Fei Hong · San Diego, US
• Zhaoqiang Zhang · Fujian, CN
• Xuxin Li · Fujian, CN

Key dates

• Filing date: Mar 17, 2020
• Grant date: Jan 11, 2022
• Expiry date: Mar 17, 2040

Classification

• Technology area (CPC —): General

Abstract

A total flavonoid extract from Gynura formosana Kitam., comprising 80-85% of rutin. A preparation method comprises selecting a complex enzyme consisting of a specific composition and ratio of enzymes for enzymatic hydrolysis, extracting and concentrating by a macroporous resin, and separating and purifying by a macroporous resin. The extract has therapeutic effect on non-alcoholic fatty liver disease.