Methods of cancer treatment using tumor antigen-specific T cells
US11219676B2 · kind B2 · utility
3Cited by
5References
19Claims
0Family size
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Key dates
| Filing date | Apr 12, 2019 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Apr 12, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application provides methods of preparing tumor antigen-specific T cells comprising enriching activated T cells from a first co-culture comprising a first population of antigen-loaded dendritic cells loaded and a population of T cells, and co-culturing the enriched activated T cells with a second population of antigen-loaded dendritic cells. Also provided are methods of treating cancer in an individual using the tumor antigen-specific T cells, pharmaceutical compositions and kits for cell-based cancer immunotherapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.