Compounds and compositions for intracellular delivery of therapeutic agents
US11220476B2 · kind B2 · utility
11Cited by
68References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 29, 2019 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Feb 17, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include a novel lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.