Cyclin dependent kinase inhibitors

US11220494B2 · kind B2 · utility

Assignee

• PFIZER INC. · US

Inventors

• Ping Chen · San Diego, US
• Sujin Cho-Schultz · San Diego, US
• Judith Gail Deal · San Diego, US
• Gary Michael Gallego · San Diego, US
• Mehran Jalaie · San Diego, US
• Robert Steven Kania · Del Mar, US
• Sajiv Krishnan Nair · San Diego, US
• Sacha Ninkovic · Village of La Jolla, US
• Suvi Tuula Marjukka Orr · San Diego, US
• Cynthia Louise Palmer · Lemon Grove, US

Key dates

• Filing date: Jul 29, 2020
• Grant date: Jan 11, 2022
• Expiry date: Jul 29, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt thereof, in which R-groups R1 to R23, A, Q, U, V, W, X, Y, Z, n, p and q are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.