Patent · US Active

Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors

US11220509B2 · kind B2 · utility

2Cited by
24References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 31, 2021
Grant dateJan 11, 2022
Priority date
Expiry dateMar 31, 2041

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds of Formula (I), or pharmaceutically, acceptable salts thereof, that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present disclosure relates to compounds, or pharmaceutically acceptable salts thereof pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds of Formula (I), or pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising compounds of Formula (I), or pharmaceutically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.