Spiro bicyclic inhibitors of menin-MLL interaction
US11220517B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Sep 13, 2017 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Sep 13, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula (I): wherein the variables have the meaning defined in the Specification. The compounds according to the present invention are useful for therapy and/or prophylaxis in a mammal, and in particular to spiro bicyclic compounds, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.