Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)
US11220524B2 · kind B2 · utility
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Key dates
| Filing date | Feb 20, 2018 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Jun 26, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The disclosure is directed to compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI: Methods of their use in inhibiting a protein arginine methyltransferase 5 (PRMT5) enzyme and treating disease, as well as methods of their preparation are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.