Patent · US Active

Procoagulant antibodies

US11220554B2 · kind B2 · utility

1Cited by

6References

26Claims

0Family size

Assignee

Novo Nordisk A/S · DK

Inventors

Karina Thorn · Farum, DK
Bjarne Gram Hansen · Copenhagen, DK
Laust Bruun Johnsen · Skodsborg, DK
Mikkel Nors Harndahl · Roskilde, DK
Zhiru Yang · Beijing, CN
Henrik Oestergaard · Søgård, DK
Per J. Greisen · Belmont, US
Eva Johansson · Mölndal, SE
Morten Groenbech Rasch · Haslev, DK
Jianhe Chen · Beijing, CN
Anders Svensson · Malmö, SE
Haisun Zhu · Norfolk, US
Rong Zhou · Fullerton, US
Prafull S. Gandhi · Rang Taché Est, DK

Key dates

Filing date	Jan 29, 2021
Grant date	Jan 11, 2022
Priority date	—
Expiry date	Jan 29, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to multispecific procoagulant antibodies capable of binding to coagulation Factor IX (FIX) and/or the activated form thereof Factor IXa (FIXa), and Factor X (FX) and/or the activated form thereof Factor Xa (FXa) and promoting FX activation by FIXa, antibodies binding their epitopes or parts thereof and methods and composition for treating subjects suffering from a coagulopathy such as haemophilia A as well as kits, methods of manufacture and methods of use.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.