Methods for preparing oligonucleotides for detecting target nucleic acid molecules in samples
US11222713B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 29, 2017 |
| Grant date | Jan 11, 2022 |
| Priority date | — |
| Expiry date | Sep 5, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6876
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to technology for preparing oligonucleotides for detecting a target nucleic acid molecule in a sample. Unlike the conventional methods, the present invention provides a first oligonucleotide candidate group designed appropriately for the first selected nucleotide sequence of the target nucleic acid molecule as a standard instead of simultaneously referring to all of the sequences exhibiting the genetic diversity. Then, an optimal oligonucleotide capable of accurately detecting a target nucleic acid molecule exhibiting genetic diversity in a sample is provided by using the first oligonucleotide candidate group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.