Compositions and methods for increasing iron intake in a mammal

US11224615B2 · kind B2 · utility

Assignee

• Solvotrin Therapeutics Limited · IE

Inventors

• John Gilmer · Dublin, IE
• Radics Gabor · Dunshaughlin, IE
• Michael Whelehan · Rathangan, IE
• Jun Wang · New City, US
• Pat O'Flynn · Cork, IE
• Mark Ledwidge · Cork, IE

Key dates

• Filing date: Mar 15, 2017
• Grant date: Jan 18, 2022
• Expiry date: Mar 15, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P7/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compositions containing iron, buffering agent and denatured protein have been prepared that are capable of increasing serum iron in a subject. For example, spray dried microbeads have been prepared containing iron entrapped within a protein matrix and unbound iron in a buffered composition that provides a gastroprotective effect, preserves iron in the more available Fe2+ form and improves iron bioavailability in humans relative to previously known vehicles for delivering iron to a subject.