Reduced leaching of a ligand
US11224858B1 · kind B1 · utility
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Key dates
| Filing date | Mar 31, 2021 |
| Grant date | Jan 18, 2022 |
| Priority date | — |
| Expiry date | Mar 31, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M1/3679
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A column for removal of a component from a fluid is disclosed. The column has a compartment with a cross sectional area. The compartment contains beads having a diameter. A ligand selected to bind to the component is coupled to the beads. The cross-sectional area and bead diameter are selected to maintain a flow velocity of the fluid within the compartment below a first threshold, thereby reducing leaching of the ligand into the fluid. Also described herein is an adsorbent comprising a ligand that is attached to a substrate by an amine bond, wherein the ligand is resistant to dissociation from the substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.