Biomarker of the colour perception of a mammal subject based on pupil frequency tagging

US11229356B2 · kind B2 · utility

Assignees

• INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE · FR
• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• Institut National de la Sante et de la Recherche Medicale (INSERM) · FR
• ASSISTANCE PUBLIQUE—HÔPITAUX DE PARIS (APHP) · FR
• Sorbonne Universite · FR

Inventors

• Pierre Pouget · Paris, FR
• Pierre Martin Jack Gérard DAYE · Braine-l'Alleud, BE
• Jean Lorenceau · Paris, FR

Key dates

• Filing date: Mar 29, 2018
• Grant date: Jan 25, 2022
• Expiry date: Mar 29, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B3/145
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Evaluation of the perception of colors by mammals with a view to obtaining a characteristic biomarker of each tested subject takes advantage of the slow pupillary oscillatory response to generate an objective neurological signature of this perception of colors. A method based on pupil frequency tagging is used at a tagging frequency Ftag adapted to the pupil response speed. A dynamic two-color stimulus is displayed, this stimulus comprising a two-color pattern the colors of which are inverted at the frequency Ftag, one of the colors gradually varying in a range of possible values. From the pupillary response, a signal representative of the oscillation power of the pupil is generated. The minimum of this signal corresponds to the relative iso-luminance of the tested pair of colors.