Patent · US Active

Compositions and methods for organ specific delivery of nucleic acids

US11229609B2 · kind B2 · utility

8Cited by

8References

39Claims

0Family size

Assignee

The Board of Regents of the University of Texas System · US

Inventors

Qiang Cheng · Shanghai, CN
Tuo WEI · Dallas, US
Daniel J. SIEGWART · Dallas, US

Key dates

Filing date	Mar 4, 2021
Grant date	Jan 25, 2022
Priority date	—
Expiry date	Mar 4, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/32
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.