Crystalline salts and polymorphs of a P2X3 antagonist
US11230533B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Apr 30, 2020 |
| Grant date | Jan 25, 2022 |
| Priority date | — |
| Expiry date | Apr 30, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are novel salts and polymorphs of 5-(2,4-diamino-pyrimidin-5-yloxy)-4-isopropyl-2-methoxy-benzenesulfonamide, which are potentially useful for modulating a condition mediated by a P2X3 or P2X2/3 receptor. Also provided are pharmaceutical formulations and methods of administration and dosing of these salts and polymorphs to subjects in need thereof.
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