Patent · US Active

KDM1A inhibitors for the treatment of disease

US11230534B2 · kind B2 · utility

3Cited by
5References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 1, 2019
Grant dateJan 25, 2022
Priority date
Expiry dateNov 1, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.