Method of generating a synthetic antibody library, said library and application(s) thereof

US11230706B2 · kind B2 · utility

Assignee

• Zumutor Biologics Inc. · US

Inventors

• Sohang Chatterjee · Kanchinakote, IN
• Kavitha Iyer Rodrigues · Savanuru, IN
• Maloy Ghosh · Kanchinakote, IN
• Sunit Maity · Kanchinakote, IN
• Divya Unnikrishnan · Kanchinakote, IN
• Yogendra Manjunath Bangalore Muniraju · Savanuru, IN
• Sathyabalan Murugesan · Bengaluru, IN
• Pavithra Mukunda · Kundapura, IN
• Bhargav Prasad · Komangalam, IN
• Veeresha Kamanagowda · Kanchinakote, IN
• Sanghamitra Bhattacharjee · Kanchinakote, IN
• Pravin Kumar Dakshinamurthy · Viralimalai, IN
• Vivek Halan · Viralimalai, IN
• Sankaranarayanan Srinivasan · Kanchinakote, IN
• Anuradha Hora · Sitapur, IN
• Bairavabalakumar Natarajan · Chennai, IN
• Karthika Nair · Survanagiri, IN
• Aswini Thanigaivel · Chennai, IN
• Maliwalave Amol · Savanuru, IN
• Bharath Ravindra Shenoy · Savanuru, IN
• Sahana Bhima Rao · Savanuru, IN
• Subhra Prakash Chakrabarty · Savanuru, IN
• Ashvini Kumar Dubey · Savanuru, IN
• Amir Khan · Aligarh, IN
• Ankurina Sharma · Savanuru, IN
• Rashmi Sharma · Edmonton, CA
• Anurag TIWARI · Sidhauli, IN
• Santosh Kumar · Burmu, IN
• Shivani Patel · Damoh, IN
• Nikitha MARKANDA · Kanchinakote, IN

Key dates

• Filing date: Jan 19, 2017
• Grant date: Jan 25, 2022
• Expiry date: Nov 14, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/60
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present disclosure relates to a method of generating an antibody library, not limiting to a synthetic antibody gene expression library built on pool of consensus nucleic acid sequences by using codon replacement technology. The present disclosure also relates to a synthetic antibody library generated by employing the method of the present disclosure and application(s) of said antibody library.