Inhibition of LET7I as a means to enhance the protective effect of progesterone against stroke
US11230711B2 · kind B2 · utility
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7Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 13, 2018 |
| Grant date | Jan 25, 2022 |
| Priority date | — |
| Expiry date | Aug 19, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention provides methods of treating neurological disease or disorder, such as brain injuries, such as stroke, traumatic brain injury (TBI), or other ischemic events that cause brain injury by inhibiting or down-regulating Let-7i activity or function. The disclosed methods may have the potential to extend the “window of opportunity” for treatment of such injuries and enhance the effectiveness of existing therapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.