Methods, systems, and compositions for counting nucleic acid molecules
US11230731B2 · kind B2 · utility
4Cited by
84References
21Claims
0Family size
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Key dates
| Filing date | Apr 2, 2019 |
| Grant date | Jan 25, 2022 |
| Priority date | — |
| Expiry date | Apr 16, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2565/537
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods, systems, and kits for detecting and quantifying variations in numbers of molecules, particularly variations in gene dosage, e.g., due to gene duplication, or to variations from the normal euploid complement of chromosomes, e.g., trisomy of one or more chromosomes that are normally found in diploid pairs, without digital sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.