Immunoassay for simultaneously screening anti-platelet antibodies and performing platelets cross matching and test apparatus for carrying out same
US11231425B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 11, 2019 |
| Grant date | Jan 25, 2022 |
| Priority date | — |
| Expiry date | Nov 15, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56977
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An immunoassay includes forming first mixtures by reacting a combination reagent with serum of a subject; simultaneously forming second mixtures by reacting randomly selected platelet samples with the serum wherein in each mixture there are immunity compounds formed by combining the platelet antigens with predetermined antibodies in the serum, and other platelet antigens and other antibodies in the serum not forming the immunity compounds; preparing an interception device including receptacles and a filter net; placing each mixture in one receptacle; washing the mixtures wherein the mixtures forming the immunity compounds are intercepted by the filter net with others passing through; adding a signal sensing reagent to each receptacle; reacting the signal sensing reagent with the intercepted mixtures forming the immunity compounds to form final products; and performing a signal sensing to determine whether the final products contain anti-platelet antibodies and determine compatibility of cross matching of respective platelet samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.