Patent · US Active

Afucosylated anti-FGFR2IIIB antibodies

US11235059B2 · kind B2 · utility

0Cited by
30References
59Claims
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Assignee

Inventors

Key dates

Filing dateNov 6, 2018
Grant dateFeb 1, 2022
Priority date
Expiry dateNov 6, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides antibodies that bind FGFR2IIIb, wherein the antibodies are afucosylated. The present invention provides compositions comprising antibodies that bind FGFR2IIIb, wherein at least 95% of the antibodies in the composition are afucosylated. In some embodiments, methods of treating cancer comprising administering afucosylated anti-FGFR2IIIb antibodies are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.