Spiro-condensed pyrrolidine derivatives as deubiquitylating enzymes (DUB) inhibitors
US11236092B2 · kind B2 · utility
0Cited by
3References
10Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 8, 2020 |
| Grant date | Feb 1, 2022 |
| Priority date | — |
| Expiry date | Apr 23, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of Cezanne 1. The invention further relates to the use of DUB inhibitors in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.