Crystal form and salt form of TGF-βRI inhibitor and preparation method therefor

US11236112B2 · kind B2 · utility

Assignee

• GenFleet Therapeutics (Shanghai) Inc. · CN

Inventors

• Lifang Wu · Shanghai, CN
• Huijun HE · Shanghai, CN
• Jianyu LU · Shanghai, CN
• Charles Z. Ding · San Mateo, US
• Lihong Hu · Shanghai, CN
• Weidong Li · Cupertino, US
• Shenyi Shi · Shanghai, CN
• Jian Li · Shanghai, CN
• Shuhui CHEN · Shanghai, CN

Key dates

• Filing date: Dec 13, 2018
• Grant date: Feb 1, 2022
• Expiry date: Dec 13, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Disclosed in the present invention are a crystal form and salt form of a TGF-βR1 inhibitor and a preparation method therefor, and further disclosed is an application of the crystal form and the salt form in preparation of medicines for treating cancers.