Divalent nucleobase compounds and uses therefor
US11236130B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jun 19, 2019 |
| Grant date | Feb 1, 2022 |
| Priority date | — |
| Expiry date | Jul 23, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5308
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Described herein are novel divalent nucleobases that each bind two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone (a genetic recognition reagent, or genetic recognition reagent). In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (γPNA) oligomer. Uses of the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.