Recombinant vector and method for producing reconstituted cytochrome P450 oxygenase-reductase fusion protein using the same
US11236309B2 · kind B2 · utility
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Key dates
| Filing date | Aug 17, 2020 |
| Grant date | Feb 1, 2022 |
| Priority date | — |
| Expiry date | Aug 17, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/0042
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A recombinant vector according to an embodiment of the present invention may be used for producing a reconstituted cytochrome P450 oxygenase-reductase fusion protein. Oxygenase and reductase may be independently expressed in a host cell into which the recombinant vector is introduced, and then may be fused with a split intein so that it is possible to increase the heme content contained in the active site of the oxygenase and improve enzyme activity and stability.
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