Patent · US Active

Heterologous production of 10-methylstearic acid by cells expressing recombinant methyltransferase

US11236373B2 · kind B2 · utility

0Cited by

1References

32Claims

0Family size

Assignee

Ginkgo Bioworks, Inc. · US

Inventors

Arthur J. Shaw, IV · Belmont, US
Hannah Blitzblau · Arlington, US
Donald V. Crabtree · Cambridge, US

Key dates

Filing date	Sep 20, 2018
Grant date	Feb 1, 2022
Priority date	—
Expiry date	Sep 20, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P7/6463
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are cells, nucleic acids, and proteins that can be used to produce branched (methyl)lipids, such as 10-methylstearic acids, and compositions that include such lipids. Cells disclosed herein comprise methyltransferase and/or reductase genes from bacteria of the class Gammaproteobacteria, which encode enzymes capable of catalyzing the production of branched (methyl)lipids from unbranched, unsaturated lipids. Saturated branched (methyl)lipids produced using embodiments of the present invention have favorable low-temperature fluidity and favorable oxidative stability, which are desirable properties for lubricants and specialty fluids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.