Patent · US Active

Time-resolved fluorescent immunochromatographic test strip for detecting paclitaxel drugs as well as preparation method and application thereof

US11237158B2 · kind B2 · utility

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5Claims
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Assignee

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Key dates

Filing dateJul 1, 2019
Grant dateFeb 1, 2022
Priority date
Expiry dateOct 26, 2039

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/52
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Some embodiments of the disclosure provide a time-resolved fluorescent immunochromatographic test strip for detecting paclitaxel drugs as well as a preparation method and application thereof. In some embodiments, the test strip includes a test paper and a sample diluent. The test paper includes a bottom plate, a sample absorption pad, a fluorescent microsphere pad, a bonding pad, and an absorbent pad. The sample absorption pad, the fluorescent microsphere pad, the bonding pad, and the absorbent pad are sequentially overlapped on the bottom plate. The fluorescent microsphere pad is sprayed with a fluorescent microsphere-labeled anti-paclitaxel monoclonal antibody. A detection area and a quality control area are immobilized on the bonding pad. The detection area is sprayed with a paclitaxel hapten-carrier protein conjugate. The quality control area is sprayed with a goat anti mouse antibody.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.