Patent · US Active

Method for detecting protein-protein interactions in a cell utilizing particle-forming polypeptide-bait fusion proteins and virus-like particles

US11237174B2 · kind B2 · utility

0Cited by

3References

11Claims

0Family size

Assignees

VIB VZW · BE
UNIVERSITEIT GENT · BE

Inventors

Jan Tavernier · Balegem, BE
Sven Eyckerman · Nazareth, BE

Key dates

Filing date	Oct 14, 2019
Grant date	Feb 1, 2022
Priority date	—
Expiry date	Jan 2, 2040

Classification

Technology area (CPC G)Physics
CPC primaryG01N2570/00
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The disclosure relates to a virus-like particle in which a protein complex is entrapped, ensuring the formation of the protein complex under physiological conditions, while protecting the protein complex during purification and identification. The disclosure further relates to the use of such virus-like particle for the isolation and identification of protein complexes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.