Methods of identifying cellular replication timing signatures and methods of use thereof
US11238956B2 · kind B2 · utility
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Key dates
| Filing date | Jun 6, 2017 |
| Grant date | Feb 1, 2022 |
| Priority date | — |
| Expiry date | Jul 5, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B40/00
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Methods for identifying and classifying differences between biological samples are based on replication timing (RT) data. By comparing RT data for a test sample(s) to RT data for already characterized samples, one can identify differences and profile any new cell type or disease. These new methods allow for the detection of all the changes between distinct samples, many of which would escape detection by previous methods that discard any features showing any intra-sample variation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.