System and methods for monitoring and improving cognitive flexibility

US11241188B2 · kind B2 · utility

Assignees

• The General Hospital Corporation · US
• TRUSTEES OF BOSTON UNIVERSITY · US

Inventors

• Alik S. Widge · Somerville, US
• Emad Eskandar · Swampscott, US
• Darin Dougherty · Wellesley, US
• Uri Tzvi Eden · Somerville, US
• Xinyi Deng · Boston, US
• Ali Yousefi · Los Angeles, US
• Angelique Paulk · Watertown, US

Key dates

• Filing date: Jun 30, 2016
• Grant date: Feb 8, 2022
• Expiry date: Mar 8, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B2560/0238
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A system and methods for monitoring and controlling a mental state of a subject are provided. In some aspects, a method includes receiving physiological and behavioral data acquired using the plurality of sensors while the subject is performing a task, and applying, using the data, a state-space framework to determine a plurality of decoder parameters correlating brain activity and behavior with a mental state of the subject. The method also includes identifying the mental state of the subject using the decoder parameters, and generating a report indicating the mental state of the subject. In some aspects, the method further includes generating, based on the identified mental state, a brain stimulation to treat a brain condition of the subject.