Patent · US Active

Monoclonal antibody specific for gamma-glutamyl-l-epsilon-lysine for the monitoring of apoptosis

US11242408B2 · kind B2 · utility

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15Claims
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Key dates

Filing dateJun 14, 2017
Grant dateFeb 8, 2022
Priority date
Expiry dateMar 25, 2039

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/26
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention concerns an ex vivo method for the monitoring of apoptosis which is based on the detection of free gamma-glutamyl-L-epsilon-Lysine (GGEL) in a biological sample of a subject with a monoclonal antibody specific to GGEL. The invention also relates to the monoclonal antibody specific to GGEL, as well as to diagnostic kits containing such a ligand.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.