Opioid for use to reduce and/or treat drug addiction
US11246865B2 · kind B2 · utility
1Cited by
7References
3Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 27, 2018 |
| Grant date | Feb 15, 2022 |
| Priority date | — |
| Expiry date | May 1, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method of treating drug addiction and reducing dependence or tolerance on a dependence-inducing opiate drug, wherein the method comprises administering to a subject a compound having the structure of formula (I): having the IUPAC name of (−)3-((S)-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)(3-thienyl)methyl)phenol, or pharmaceutically acceptable esters or salts thereof, wherein the compound has activity on the mu, delta and kappa opioid receptors thereby providing added analgesia with an improved therapeutic index and reduced risk of respiratory depression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.