Meditopes and meditope-binding antibodies and uses thereof

US11246942B2 · kind B2 · utility

Assignee

• City of Hope · US

Inventors

• John C. Williams · Duarte, US
• David Horne · Duarte, US
• Yuelong Ma · Duarte, US
• Heng Wei Chang · Foster City, US
• Joshua M. Donaldson · Chambersburg, US
• Cindy Zer · Duarte, US
• Krzysztof Bzymek · Pasadena, US
• Kendra N. Avery · Pasadena, US
• Jun Xie · Singapore, SG

Key dates

• Filing date: Jun 5, 2017
• Grant date: Feb 15, 2022
• Expiry date: Jun 5, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antibodies and meditopes that bind to the antibodies are provided, as well as complexes, compositions and combinations containing the meditopes and antibodies, and methods of producing, using, testing, and screening the same, including therapeutic and diagnostic methods and uses.