Compound and use thereof in synthesis of brivaracetam intermediate and crude drug
US11247977B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 20, 2019 |
| Grant date | Feb 15, 2022 |
| Priority date | — |
| Expiry date | Jun 20, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present application provides a compound in formula III, and further provides a use of the compound in the synthesis of a Brivaracetam intermediate and a crude drug, and a synthesis method. A raw material involved in the method of the present application is low in costs and easily available; (R)-4-propyl-dihydrofuran-2-ketone having high optical purity can be prepared; complicated separation and purification steps are avoided; costs are reduced, and the method is more applicable to industrial production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.