Patent · US Active

Antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor

US11248052B2 · kind B2 · utility

1Cited by
52References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 22, 2019
Grant dateFeb 15, 2022
Priority date
Expiry dateApr 13, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y302/01031
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compositions and methods relating to or derived from antigen binding proteins capable of inducing β-Klotho, and or FGF21-like mediated signaling. In embodiments, the antigen binding proteins specifically bind to a complex comprising β-Klotho and at least one of (i) FGFR1c, (ii) FGFR2c and (iii) FGFR3c.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.