Patent · US Active

Method of RNA in vitro transcription using a buffer containing a dicarboxylic acid or tricarboxylic acid or a salt thereof

US11248223B2 · kind B2 · utility

23Cited by

3References

29Claims

0Family size

Assignee

CureVac AG · DE

Inventors

Benyamin YAZDAN PANAH · Tübingen, DE
Aniela WOCHNER · Tübingen, DE
Tilmann ROOS · Aspenhausiedlung, DE
Andreas FUNKNER · Tübingen, DE
Martin Kunze · Rottenburg am Neckar, DE

Key dates

Filing date	Dec 23, 2016
Grant date	Feb 15, 2022
Priority date	—
Expiry date	Aug 22, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6844
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a buffer system comprising a dicarboxylic acid or tricarboxylic acid or a salt thereof for synthesizing RNA molecules as well as a method of RNA in vitro transcription using this buffer system. The present invention also provides the use of this buffer system in RNA in vitro transcription and in the reduction or prevention of precipitates during RNA in vitro transcription.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.