Dialysis based invitro drug release study method
US11249056B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2021 |
| Grant date | Feb 15, 2022 |
| Priority date | — |
| Expiry date | Mar 17, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/146
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to dialysis based in vitro drug release study method which mainly involves the use of a dialysis cartridge (A), a dissolution vessel (B), a receiver media vessel (C) and tubing's on the inlet and outlet ports (D, E, F, G) of the cartridge. When the pharmaceuticals complex dosage form is added to the dissolution vessel, diffusion of the soluble drug through the membrane of the dissolution cartridge assists in determining the release of drug from the complex dosage form. This study can be done by various methods as required by the complex dosage form. If the dosage form needs to go through dissolution followed by diffusion, the setup as described in Experiment 1 is arranged and the study is performed accordingly and if the dosage form needs to go through diffusion step only, the setup as described in Experiment 2 is arranged and the study is performed accordingly.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.