Patent · US Active

Composition comprising highly-concentrated ALPHA1 proteinase inhibitor and method for obtaining thereof

US11253578B2 · kind B2 · utility

0Cited by

5References

16Claims

0Family size

Assignee

GRIFOLS WORLDWIDE OPERATIONS LIMITED · IE

Inventors

James Rebbeor · Garner, US
Charles Miller · Apex, US
Anthony Klos · Raleigh, US
Eric Allgaier · Wake Forest, US
Thomas P. Zimmerman · Raleigh, US
Kevin Wee · Wake Forest, US
Michelle StPeter · Garner, US
Kelly Glancy · Holly Springs, US

Key dates

Filing date	Aug 1, 2019
Grant date	Feb 22, 2022
Priority date	—
Expiry date	Aug 1, 2039

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/0073
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compositions include highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) in a concentration greater than or equal to 100 mg/ml. Pharmaceutical compositions can be prepared from these compositions. The pharmaceutical compositions can be suitable for subcutaneous administration. The highly-concentrated A1PI solutions can be obtained by single-pass tangential flow filtration (SPTFF).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.