Polymer hydrogels for in vivo applications and methods for using and preparing same
US11253597B2 · kind B2 · utility
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Key dates
| Filing date | Jul 3, 2018 |
| Grant date | Feb 22, 2022 |
| Priority date | — |
| Expiry date | Aug 16, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are described for a polymer hydrogel created by a cycloaddition reaction between an azide and an alkyne that proceeds rapidly without catalyst to produce the polymer hydrogel in less than ninety seconds. The polymer hydrogel can be used in in vivo applications for the localized delivery of therapeutic agent in aqueous solutions. An example of therapeutic delivery of a protein in a mouse model is demonstrated.
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