Patent · US Active

Crystalline forms of N-(4-(4-(cyclopropymethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide

US11254652B2 · kind B2 · utility

2Cited by

1References

8Claims

0Family size

Assignee

Agios Pharmaceuticals, Inc. · US

Inventors

Jacob P. Sizemore · Cambridge, US
Liting Guo · Suzhou, CN
Mahmoud Mirmehrabi · Halifax, CA
Yeqing Su · Halifax, CA

Key dates

Filing date	Nov 21, 2018
Grant date	Feb 22, 2022
Priority date	—
Expiry date	Nov 21, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein are amorphous and crystalline hemisulfate salt forms of the formula (I). Also provided are pharmaceutical compositions comprising the amorphous and crystalline hemisulfate salt forms, methods for their manufacture, and uses thereof for treating conditions associated with pyruvate kinase such as e.g., pyruvate kinase deficiency.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.