Quinoline derivatives for treating infections with helminths

US11254661B2 · kind B2 · utility

Assignee

• Bayer Animal Health GmbH · DE

Inventors

• Nils Griebenow · Milford, US
• Wei Zhuang · Monheim, DE
• Daniel KULKE · Leverkusen, DE
• Claudia Böhm · Hannover, DE
• Hans-Georg Schwarz · Dorsten, DE
• Walter Hubsch · Wuppertal, DE
• Thomas ILG · Monheim, DE

Key dates

• Filing date: Jul 30, 2018
• Grant date: Feb 22, 2022
• Expiry date: Jul 30, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention covers quinoline compounds of general formula (I), in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.